An experiment that involved Drosophila fruit flies being raised in outer space at the Space Shuttle Discovery showed that the flies have a weaker immune system compared to regular Drosophila flies raised on Earth.
The flies were sent into space aboard the Space Shuttle Discovery as eggs. It takes about 10 days for the flies to develop into adults and after the return trip, scientists found that the space flies had a weak immune response system to fungus. However, the immune system reacted normally to bacteria.
Scientists noted that the flies also showed a high expression of heat-shock protein genes that moderate the Toll pathway which mediates fungus infections. They also believe that aside from the heat-shock proteins, microgravity could also interfere with the protein behaviors outside the cell which are important for Toll pathway signalling.
The 12 day space mission brings to light the link between gravity and the immune system.
The flies were sent into space aboard the Space Shuttle Discovery as eggs. It takes about 10 days for the flies to develop into adults and after the return trip, scientists found that the space flies had a weak immune response system to fungus. However, the immune system reacted normally to bacteria.
Scientists noted that the flies also showed a high expression of heat-shock protein genes that moderate the Toll pathway which mediates fungus infections. They also believe that aside from the heat-shock proteins, microgravity could also interfere with the protein behaviors outside the cell which are important for Toll pathway signalling.
The 12 day space mission brings to light the link between gravity and the immune system.